![]() Extensive efforts are underway to find specific vaccines and antivirals against SARS-CoV-2. Acute respiratory distress syndrome is also strongly associated with mortality.Ĭonclusions and Relevance Coronavirus disease 2019 is associated with a high inflammatory burden that can induce vascular inflammation, myocarditis, and cardiac arrhythmias. Acute cardiac injury determined by elevated high-sensitivity troponin levels is commonly observed in severe cases and is strongly associated with mortality. Factors associated with mortality include male sex, advanced age, and presence of comorbidities including hypertension, diabetes mellitus, cardiovascular diseases, and cerebrovascular diseases. A large proportion of patients have underlying cardiovascular disease and/or cardiac risk factors. ![]() Observations Coronavirus disease 2019 can cause a viral pneumonia with additional extrapulmonary manifestations and complications. We review the basics of coronaviruses, with a focus on COVID-19, along with their effects on the cardiovascular system. Coronaviruses are known to affect the cardiovascular system. Importance Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19) has reached a pandemic level.
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